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members:tristan.moreau:index [2014/09/01 15:16]
tmoreau
members:tristan.moreau:index [2015/03/27 10:44] (current)
nbuisard
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-====== ​Research Area : Emergence of a formal semantic description of cortical territories====== +====== ​PhD thesis ​: Emergence of a formal semantic description of human connectomics====== 
-Subdividing the cortex into structural elementsknown as **parcellation**is a key aspect to apprehend the link between structure and function in the brain. One of the main issue of parcellation is the compilation of the human cerebral **connectome** and could have important medical applications as better identify important fonctional areas to preserve in neurosurgery.+=== Keywords === 
 +NeuroinformaticsIRM, connectome, tractography,​ connectivity-based parcellation,​ web semantic, ontology, clustering.
  
-Different aspects of cerebral **structural connectivity** were investigated in this thesis using **diffusion magnetic resonance imaging** (MRI) and **tractography**. ​  +== Abstract ==
  
-  * A first study aimed to characterise short association bundles in the central region ​based on **diffusion tensor imaging** (DTI)+Subdividing the cortex into structural elements, known as **parcellation**,​ is a key aspect to apprehend the link between structure and function in the brain. One of the main issue of parcellation is the compilation of the human cerebral **connectome** and could have important medical applications in medical image as better identify important functional areas to preserve in neurosurgery. 
-  * A second study aimed to use structural connectivity relation ​to define a **connectivity-based-parcellation** using a **spectral clustering**.+ 
 +Different aspects of human cerebral **structural connectivity** were investigated in this thesis using **diffusion Magnetic Resonance Imaging** (dMRI) and **tractography**,​ which is currently the unique technique that could reconstruct structural connectivity in vivo and non invasively. ​  ​ 
 + 
 +  ​* A first study aimed to characterise short association bundles in the central region ​using a deterministic tractograhy
 +  * A second study aimed to define a **connectivity-based-parcellation** using probabilistic tractography.
   * Finally, the purpose of the last study was to create an applicative **ontology** in order to produce **semantic annotations** of connectional fingerprints based on **probabilistic tractography**.   * Finally, the purpose of the last study was to create an applicative **ontology** in order to produce **semantic annotations** of connectional fingerprints based on **probabilistic tractography**.
  
 +This thesis gave me the opportunity to develop of **a neuroimaging tool box** called **taopy** (cf : [[:​software|Software developpment]]).
  
-This thesis gave me the opportunity to contribute to the developpment of **a neuroimaging tool box** called **taopy** (cf [[:software|Software developpment]]).+== Deterministic tractography in the central area == 
 +{{:members:tristan.moreau:​bundle.png|}}
  
-{{:​members:​tristan.moreau:​high-resolution.png|}}+== Probabilistic tractography of corpus callosum ==
 {{:​members:​tristan.moreau:​diffusion.png|}} {{:​members:​tristan.moreau:​diffusion.png|}}
 {{:​members:​tristan.moreau:​tracto.png|}} {{:​members:​tristan.moreau:​tracto.png|}}
 +
 +== High-resolution cortical parcellation ==
 +{{:​members:​tristan.moreau:​high-resolution.png|}}
 +
 +== Connectivity-based parcellation of SMA/pre-SMA ==
 {{:​members:​tristan.moreau:​ba6.png|}} {{:​members:​tristan.moreau:​ba6.png|}}
-{{:​members:​tristan.moreau:​vsparql1.png|}}+ 
 +== Connectivity-based parcellation of Broca areas == 
 +{{:​members:​tristan.moreau:​broca_connectivity_based_parcellation.png|}} 
 + 
 +== Example of a vSparQL query on the reference ontology Foundational Model of Anatomy (FMA)== 
 +{{:​members:​tristan.moreau:​vpsarql_query.png|}}
  
 ====== Teaching 2013-2014 at université Rennes1 ====== ====== Teaching 2013-2014 at université Rennes1 ======
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 ====== Publications ====== ====== Publications ======
 +  * Tristan Moreau, Bernard Gibaud, Ontology-based approach for in vivo human connectomics:​ the medial Brodmann area 6 case study, Fontiers in Neuroinformatics,​ 2015.
   * Elsa Magro, Tristan Moreau, Romuald Seizeur, Ilyess Zemmoura, Bernard Gibaud and Xavier Morandi. **Connectivity within the primary motor cortex:a DTI tractography study**, Surgical and Radiologic Anatomy,​2014,​36,​125-135,​http://​dx.doi.org/​10.1007/​s00276-013-1160-y ​   * Elsa Magro, Tristan Moreau, Romuald Seizeur, Ilyess Zemmoura, Bernard Gibaud and Xavier Morandi. **Connectivity within the primary motor cortex:a DTI tractography study**, Surgical and Radiologic Anatomy,​2014,​36,​125-135,​http://​dx.doi.org/​10.1007/​s00276-013-1160-y ​
   * Tristan Moreau, Bernard Gibaud. **Connectivity-based parcellation of the    * Tristan Moreau, Bernard Gibaud. **Connectivity-based parcellation of the 
inserm rennes1 ltsi