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--- members:tristan.moreau:index [2014/09/29 13:56]
tmoreau
+++ members:tristan.moreau:index [2015/03/27 10:44] (current)
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 ====== PhD thesis : Emergence of a formal semantic description of human connectomics======
-===== Abstract =====
+=== Keywords ===
+Neuroinformatics, IRM, connectome, tractography, connectivity-based parcellation, web semantic, ontology, clustering.
+== Abstract ==
 Subdividing the cortex into structural elements, known as **parcellation**, is a key aspect to apprehend the link between structure and function in the brain. One of the main issue of parcellation is the compilation of the human cerebral **connectome** and could have important medical applications in medical image as better identify important functional areas to preserve in neurosurgery.
@@ Line 22: / Line 25: @@
 Different aspects of human cerebral **structural connectivity** were investigated in this thesis using **diffusion Magnetic Resonance Imaging** (dMRI) and **tractography**, which is currently the unique technique that could reconstruct structural connectivity in vivo and non invasively.
-  * A first study aimed to characterise short association bundles in the central region based on **diffusion tensor imaging** (DTI).
+  * A first study aimed to characterise short association bundles in the central region using a deterministic tractograhy.
-  * A second study aimed to use structural connectivity to define a **connectivity-based-parcellation**.
+  * A second study aimed to define a **connectivity-based-parcellation** using probabilistic tractography.
   * Finally, the purpose of the last study was to create an applicative **ontology** in order to produce **semantic annotations** of connectional fingerprints based on **probabilistic tractography**.
-This thesis gave me the opportunity to contribute to the developpment of **a neuroimaging tool box** called **taopy** (cf : [[:software|Software developpment]]).
+This thesis gave me the opportunity to develop of **a neuroimaging tool box** called **taopy** (cf : [[:software|Software developpment]]).
-===== Few results =====
+== Deterministic tractography in the central area ==
+{{:members:tristan.moreau:bundle.png|}}
-{{:members:tristan.moreau:high-resolution.png|}}
+== Probabilistic tractography of corpus callosum ==
 {{:members:tristan.moreau:diffusion.png|}}
 {{:members:tristan.moreau:tracto.png|}}
+== High-resolution cortical parcellation ==
+{{:members:tristan.moreau:high-resolution.png|}}
+== Connectivity-based parcellation of SMA/pre-SMA ==
 {{:members:tristan.moreau:ba6.png|}}
-{{:members:tristan.moreau:vsparql1.png|}}
-{{:members:tristan.moreau:bundle.png|}}
+== Connectivity-based parcellation of Broca areas ==
+{{:members:tristan.moreau:broca_connectivity_based_parcellation.png|}}
+== Example of a vSparQL query on the reference ontology Foundational Model of Anatomy (FMA)==
+{{:members:tristan.moreau:vpsarql_query.png|}}
 ====== Teaching 2013-2014 at université Rennes1 ======
@@ Line 65: / Line 77: @@
 ====== Publications ======
+  * Tristan Moreau, Bernard Gibaud, Ontology-based approach for in vivo human connectomics: the medial Brodmann area 6 case study, Fontiers in Neuroinformatics, 2015.
   * Elsa Magro, Tristan Moreau, Romuald Seizeur, Ilyess Zemmoura, Bernard Gibaud and Xavier Morandi. **Connectivity within the primary motor cortex:a DTI tractography study**, Surgical and Radiologic Anatomy,2014,36,125-135,http://dx.doi.org/10.1007/s00276-013-1160-y
   * Tristan Moreau, Bernard Gibaud. **Connectivity-based parcellation of the