Christian Barillot, Germain Forestier, Bernard Gibaud, Franck Michel, Tristan Moreau, Guillaume Renard, Bacem Wali

Our vision is illustrated on the figure below. It consists in annotating image data and all features derived from this data (imaging biomarkers, patient specific models) in reference to domain ontologies that will make their semantics explicit. This will facilitate wide-scale intra- et inter-domain sharing and re-use of the data, as needed in modern translational research, thanks to semantic web technologies and mediation infrastructures based on these technologies.




Our works address two basic aspects of this vision : the design of mediation infrastructures, and the semantic annotation of images. Two major different topics have been reached in the period:

• Sharing of data and sharing of processing tools in neuroimaging (Neurobase and Neurolog projects)} which led to build a suitable architecture to share images and processing tools, started from the NeuroBase project (supported by the French Ministry of Research), and pursued by the Neurolog project (project supported by ANR) More ...
• Semantic annotation of brain anatomical structures in MRI images, which aimed at demonstrating how ontologies can be used also as knowledge sources supporting knowledge-based image annotation software More ...

• Both Neurobase and Neurolog are collaborative ANR projects. The partners with whom we have the tightest relations are: I3S (Sophia) and Business Objects, for WP1 and WP4; MIS (Amiens), GIN (Grenoble) and Pitié-Salpêtrière (Paris) for WP2; GIN (Grenoble) and Pitié-Salpetrière (Paris) for WP5.
• Concerning the second topic, the work was done in collaboration with Christine Golbreich from the University of Versailles Saint Quentin, also member of LIRMM/CNRS in Montpellier

• Concerning the first topic, the external support for this project was brought by ANR (Agence National de la Recherche), through grant ANR-06-TLOG-024
• ANR VIP: New ANR project accepted in 2009 in collaboration with CREATIS/INSERM Lyon. A significant part of this project deals with ontology development to support the sharing of models, simulated data and the interoperability of simulation software components
• Concerning the second topic, the work did not receive support from national research agencies, yet. However it received support from INRIA through the “”internship program“” (Abdallah Miladi, Souheil Selmi, Tasnim Bouzgarrou)