Email: delphine.tanguy@univ-rennes1.fr
Address:
MediCIS - LTSI UMR1099 INSERM
Faculté de Médecine, Université de Rennes 1
2 avenue du Prof. Léon Bernard
35043 Rennes cedex - France
Assistant: Noemie Buisard : +33 2 23 23 69 30

Neurosciences, Ethology, Dementias
PhD project: Neural basis of disinhibition in neurodegenerative diseases
Collaboration:
FrontLab
Institut du Cerveau et de la Moelle épinière UMR_S 1127/UMR 7225
47 Boulevard de l'hôpital
75013 Paris

Inhibition troubles occur in several neurodegenerative diseases, such as Alzheimer's disease, behavioral variant frontotemporal dementia or Parkinson's disease. These disorders affecting the daily lives of patients are also known to be a major cause of distress for caregivers. However, neural correlates of disinhibition are still poorly known and management remains limited.
The main objective of my PhD project is to study behavioural and cognitive disinhibition in bvFTD and AD patients through a semi-ecological task, a neuropsychological assessment and MRI analyses. The aim is to differentiate between different sub-forms of disinhibition associated with different neural network impairments.

Assessing disinhibition behaviour in behavioural variant frontotemporal dementia patients using ecological and cognitive tasks
Measuring Behavior 2018 - Manchester