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+++ members:tristan.moreau:index [2014/09/29 14:41]
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 ====== PhD thesis : Emergence of a formal semantic description of human connectomics======
-===== Context =====
+=== Keywords ===
+Neuroinformatics, IRM, connectome, tractography, connectivity-based parcellation, web semantic, ontology, clustering.
-Subdividing the cortex into structural elements, known as **parcellation**, is a key aspect to apprehend the link between structure and function in the brain. One of the main issue of parcellation is the compilation of the human cerebral **connectome** and could have important medical applications in medical image as better identify important fonctional areas to preserve in neurosurgery.
+== Abstract ==
-Different aspects of cerebral **structural connectivity** were investigated in this thesis using **diffusion Magnetic Resonance Imaging** (dMRI) and **tractography**, which is currently the unique technique that could reconstruct structural connectivity in vivo and non invasively.
+Subdividing the cortex into structural elements, known as **parcellation**, is a key aspect to apprehend the link between structure and function in the brain. One of the main issue of parcellation is the compilation of the human cerebral **connectome** and could have important medical applications in medical image as better identify important functional areas to preserve in neurosurgery.
-  * A first study aimed to characterise short association bundles in the central region based on **diffusion tensor imaging** (DTI).
+Different aspects of human cerebral **structural connectivity** were investigated in this thesis using **diffusion Magnetic Resonance Imaging** (dMRI) and **tractography**, which is currently the unique technique that could reconstruct structural connectivity in vivo and non invasively.
-  * A second study aimed to use structural connectivity to define a **connectivity-based-parcellation**.
+  * A first study aimed to characterise short association bundles in the central region using a deterministic tractograhy.
+  * A second study aimed to define a **connectivity-based-parcellation** using probabilistic tractography.
   * Finally, the purpose of the last study was to create an applicative **ontology** in order to produce **semantic annotations** of connectional fingerprints based on **probabilistic tractography**.
+This thesis gave me the opportunity to develop of **a neuroimaging tool box** called **taopy** (cf : [[:software|Software developpment]]).
+== Deterministic tractography in the central area ==
+{{:members:tristan.moreau:bundle.png|}}
+== Probabilistic tractography of corpus callosum ==
-This thesis gave me the opportunity to contribute to the developpment of **a neuroimaging tool box** called **taopy** (cf : [[:software|Software developpment]]).
-{{:members:tristan.moreau:high-resolution.png|}}
 {{:members:tristan.moreau:diffusion.png|}}
 {{:members:tristan.moreau:tracto.png|}}
+== High-resolution cortical parcellation ==
+{{:members:tristan.moreau:high-resolution.png|}}
+== Connectivity-based parcellation of SMA/pre-SMA ==
 {{:members:tristan.moreau:ba6.png|}}
-{{:members:tristan.moreau:vsparql1.png|}}
-{{:members:tristan.moreau:bundle.png|}}
+== Connectivity-based parcellation of Broca areas ==
+{{:members:tristan.moreau:broca_connectivity_based_parcellation.png|}}
+== Example of a vSparQL query on the reference ontology Foundational Model of Anatomy (FMA)==
+{{:members:tristan.moreau:vpsarql_query.png|}}
 ====== Teaching 2013-2014 at université Rennes1 ======